Hydrochloric Acid → 5-{6-[2-(2-chloro-6-fluoro-phenyl)-ethylamino]-2-methylsulfanyl-pyrimidin-4-yl}-1H-pyridin-2-one

反応式

[CH3:29][CH2:30][OH:31].[Cl:1][c:2]1[c:3]([CH2:9][CH2:10][NH:11][c:12]2[n:13][c:14]([S:26][CH3:27])[n:15][c:16](-[c:18]3[cH:19][n:20][c:21]([O:24][CH3:25])[cH:22][cH:23]3)[cH:17]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1.[ClH:28]>>[Cl:1][c:2]1[c:3]([CH2:9][CH2:10][NH:11][c:12]2[n:13][c:14]([S:26][CH3:27])[n:15][c:16](-[c:18]3[cH:19][nH:20][c:21](=[O:24])[cH:22][cH:23]3)[cH:17]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1

参加物

反応物 3

HCID 313Hydrochloric Acid

HCID 702Ethanol

HCID 11553210[2-(2-Chloro-6-fluoro-phenyl)-ethyl]-[6-(6-methoxy-pyridin-3-yl)-2-methylsulfanyl-pyrimidin-4-yl]-amine

生成物 1

HCID 115455985-{6-[2-(2-chloro-6-fluoro-phenyl)-ethylamino]-2-methylsulfanyl-pyrimidin-4-yl}-1H-pyridin-2-one

出典と根拠

ORDレコード: ord-c61b8d61d2e5439fb713a42bd4e6979d
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…