2-(Chloromethyl)-4-fluoro-1-(trifluoromethyl)benzene → 6-[4-(5-FLUORO-2-TRIFLUOROMETHYLBENZYL)PIPERAZIN-1-YL]PYRIDAZINE-3-CARBOXYLIC Acid (2-CYCLOPROPYLETHYL)AMIDE

反応式

[CH:14]1([CH2:17][CH2:18][NH:19][C:20](=[O:21])[c:22]2[n:23][n:24][c:25]([N:28]3[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]3)[cH:26][cH:27]2)[CH2:15][CH2:16]1.[F:1][c:2]1[cH:3][cH:4][c:5]([C:10]([F:11])([F:12])[F:13])[c:6]([CH2:7][Cl:8])[cH:9]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:10]([F:11])([F:12])[F:13])[c:6]([CH2:7][N:31]2[CH2:30][CH2:29][N:28]([c:25]3[n:24][n:23][c:22]([C:20]([NH:19][CH2:18][CH2:17][CH:14]4[CH2:15][CH2:16]4)=[O:21])[cH:27][cH:26]3)[CH2:33][CH2:32]2)[cH:9]1

参加物

反応物 2

HCID 27591692-(Chloromethyl)-4-fluoro-1-(trifluoromethyl)benzene

HCID 66849327N-(2-cyclopropylethyl)-6-(1-piperazinyl)-3-pyridazinecarboxamide

生成物 1

HCID 112594926-[4-(5-FLUORO-2-TRIFLUOROMETHYLBENZYL)PIPERAZIN-1-YL]PYRIDAZINE-3-CARBOXYLIC Acid (2-CYCLOPROPYLETHYL)AMIDE

出典と根拠

ORDレコード: ord-c4a09734b495427fb2de03eb64cd569a
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…