Methanol → 1-(6-Amino-pyridin-2-ylmethyl)-3-(4-methoxy-3-methyl-benzoyl)-1H-quinolin-4-one

反応式

[CH2:37]([NH:38][CH2:39][CH3:40])[CH3:41].[CH3:42][OH:43].[F:1][C:2]([F:3])([F:4])[C:35]([NH:5][c:6]1[n:7][c:8]([CH2:12][n:13]2[cH:14][c:15]([C:24]([c:25]3[cH:26][c:27]([CH3:33])[c:28]([O:31][CH3:32])[cH:29][cH:30]3)=[O:34])[c:16](=[O:23])[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]23)[cH:9][cH:10][cH:11]1)=[O:36]>>[NH2:5][c:6]1[n:7][c:8]([CH2:12][n:13]2[cH:14][c:15]([C:24]([c:25]3[cH:26][c:27]([CH3:33])[c:28]([O:31][CH3:32])[cH:29][cH:30]3)=[O:34])[c:16](=[O:23])[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]23)[cH:9][cH:10][cH:11]1

参加物

反応物 3

HCID 887Methanol

HCID 8021Diethylamine

HCID 577547792,2,2-Trifluoro-N-{6-[3-(4-methoxy-3-methyl-benzoyl)-4-oxo-4H-quinolin-1-ylmethyl]-pyridin-2-yl}-acetamide

生成物 1

HCID 577545401-(6-Amino-pyridin-2-ylmethyl)-3-(4-methoxy-3-methyl-benzoyl)-1H-quinolin-4-one

出典と根拠

ORDレコード: ord-892ac0beb478430f891a722be1ba1f3c
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…