反応式
C1CCC(N=C=N[CH:10]2[CH2:15][CH2:14]CCC2)CC1.C(O)[C@H](O)[C@H]1[O:23][C:21](=[O:22])[C:20](O)=[C:19]1O.[CH3:28]N(C=O)C>>[C:21]([O:23][C:15]([CH3:14])([CH3:10])[CH3:28])(=[O:22])[CH2:20][CH3:19]参加物
4
実験手順
108-Cascade:methane[4]:(3-oxo-6-oxa-2-azaheptylidyne):(3-oxo-2-azapentylidyne)2 :tert-butyl propanoate (22) was prepared (48%), as a spongy white solid from 36-acid 17 (2.63 g, 643 μmol), amine 2 (10.10 g, 24.3 mmol), DCC (5.00 g, 24.3 mmol), 1-HBT (3.28 g, 24.3 mmol), and DMF (150 mL) via Procedure A: 5.68 g; mp 103°-108° C. ; 1H NMR δ1.43 (s, CH3, 972H), 1.95, 2.19 (br, CH2, 624H); 3C NMR δ28.1 (CH3), 29,7 (CH2CH2), 57.3 (4°CNH), 80.3 (CMe3), 170.8 (CONH), 172.7 (CO2); IR 3366 (NH), 1730 (ester C=O), 1645 (amide C=O), 1160 (ester C--O) cm-1. Anal. Calcd for C969H1,672 N 52 O272 : C, 63.24; H, 9.16; N. 3.96. Found: C, 63.06; H, 8.89; N, 4.23.
出典と根拠
- ORDレコード
- ord-9103e8d7e7a541cb80b623691f21a765
- 出典データセット
- uspto-grants-1995_06
- 特許番号
- US05422379
関連ノート
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