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(R)-(+)-1,1,1-trifluoro-2-octyl 4-benzyloxybenzoate → 4-hydroxybenzoic acid (R)-1-trifluoromethyl-heptyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (R)-(+)-1,1,1-trifluoro-2-octyl 4-benzyloxybenzoate | HCID 22850730 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 4-hydroxybenzoic acid (R)-1-trifluoromethyl-heptyl ester | HCID 14549217 | — |
反応手順
To a solution of the compound obtained in (1) above (3.8 g) in methanol (100 ml), was added 10% Pd on carbon (0.4 g). The mixture was subjected to hydrogenation in an atmosphere of hydrogen to obtain the titled compound (2.8 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05424005 |
| 出典データセット | uspto-grants-1995_06 |
| ORD ID | ord-fbe288e2989d4a03b569285ac19ab96c |
| 出典メモ | uspto-grants-1995_06 |