Dichloromethane → 4-[5-(4-Aminothieno[2,3-d]pyrimidin-6-yl)-1-methyl-1H-imidazol-4-yl]phenol

反応式

[B:1]([Br:2])([Br:3])[Br:4].[CH3:5][O:6][c:7]1[cH:8][cH:9][c:10](-[c:13]2[n:14][cH:15][n:16]([CH3:28])[c:17]2-[c:18]2[cH:19][c:20]3[c:21]([n:22][cH:23][n:24][c:25]3[NH2:26])[s:27]2)[cH:11][cH:12]1.[Cl:29][CH2:30][Cl:31]>>[OH:6][c:7]1[cH:8][cH:9][c:10](-[c:13]2[n:14][cH:15][n:16]([CH3:28])[c:17]2-[c:18]2[cH:19][c:20]3[c:21]([n:22][cH:23][n:24][c:25]3[NH2:26])[s:27]2)[cH:11][cH:12]1

参加物

反応物 3

HCID 6344Dichloromethane

HCID 25134Boron tribromide

HCID 691973206-[4-(4-Methoxyphenyl)-1-methyl-1H-imidazol-5-yl]thieno[2,3-d]pyrimidin-4-amine

生成物 1

HCID 102456254-[5-(4-Aminothieno[2,3-d]pyrimidin-6-yl)-1-methyl-1H-imidazol-4-yl]phenol

出典と根拠

ORDレコード: ord-6391a6dfce5845d7b8223c58b31b8313
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…