1-Propanesulfonyl chloride, 2-methyl- → 8-(2-Methyl-propane-1-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione

反応式

[CH3:24][CH:25]([CH2:26][S:27](=[O:28])(=[O:29])[Cl:30])[CH3:31].[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([N:10]2[C:11](=[O:21])[C:12]3([CH2:13][CH2:14]2)[CH2:15][C:16](=[O:20])[NH:17][CH2:18][CH2:19]3)[cH:8][cH:9]1)([F:22])[F:23]>>[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([N:10]2[C:11](=[O:21])[C:12]3([CH2:13][CH2:14]2)[CH2:15][C:16](=[O:20])[N:17]([S:27]([CH2:26][CH:25]([CH3:24])[CH3:31])(=[O:28])=[O:29])[CH2:18][CH2:19]3)[cH:8][cH:9]1)([F:22])[F:23]

参加物

反応物 2

HCID 1822361-Propanesulfonyl chloride, 2-methyl-

HCID 584784112-(4-Trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione

生成物 1

HCID 534826238-(2-Methyl-propane-1-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione

出典と根拠

ORDレコード: ord-b8d3e2b0fadc492f8622a8f7f7dbdd28
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…