Acetate → 2-Chloro-5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)pyrimidine

反応式

[Br:1][c:2]1[cH:3][n:4][c:5]([Cl:8])[n:6][cH:7]1.[CH3:41][OH:42].[F-:30].[F:9][C:10]1([F:29])[O:11][c:12]2[c:13]([cH:15][c:16]([CH3:28])[c:17]([B:19]3[O:20][C:21]([CH3:22])([CH3:23])[C:24]([CH3:25])([CH3:26])[O:27]3)[cH:18]2)[O:14]1.[K+:31].[O-:33][C:34]([CH3:35])=[O:36].[O-:37][C:38]([CH3:39])=[O:40].[Pd+2:32]>>[c:2]1(-[c:17]2[c:16]([CH3:28])[cH:15][c:13]3[c:12]([cH:18]2)[O:11][C:10]([F:9])([F:29])[O:14]3)[cH:3][n:4][c:5]([Cl:8])[n:6][cH:7]1