化工社化工社 化学情報印刷レポート · 研究参考用
Acetyl chloride → Acetoacetic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetyl chloride | HCID 6367 | — |
| 反応物 | 4-Cyclopentene-1,3-diol | HCID 278600 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | Acetoacetic Acid | HCID 96 | — |
| 生成物 | Acetate | HCID 175 | — |
反応手順
Forty-eight milligrams (0.6 mmol) of acetic acid chloride was added to a mixture of 111 milligrams (1.1 mmols) of 3,5-dihydroxycyclopent-1-ene and 0.5 milliliter of pyridine with stirring over a period of 5 hours. The aftertreatment was carried out as in Example 1, and 62 milligrams of a crude product was obtained. When calculations were made from the results of the chromatographic analysis, the yields of the monoacetate and diacetate were 22% and 7%, respectively.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04132726 |
| 出典データセット | uspto-grants-1979_01 |
| ORD ID | ord-74caa85771d14bb395005263366e74cf |
| 出典メモ | uspto-grants-1979_01 |