Ethylenediamine → HCID 12632114、化合物

HRID 2163674ノート

反応式

HRID 2163674 の反応式
[C:1]1([C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)([CH3:10])C#N)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:17]([NH2:20])[CH2:18][NH2:19].S([C:25]1C=CC(C)=CC=1)([O-])(=O)=O>>[C:11]1([CH:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH2:10][C:25]2[NH:19][CH2:18][CH2:17][N:20]=2)[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

参加物

4

反応物 3

HCID 3301EthylenediamineHCID 796772,2-DiphenylpropiononitrileHCID 85570p-Toluenesulfonate

生成物 1

HCID 12632114HCID 12632114、化合物

実験手順

A mixture of 2.07 g of 2,2-diphenyl propionitrile and 2.78 g of ethylenediamine.tosylate was heated at 200° C. for 3 hours. After cooling, the solution was rendered basic with an alkali hydroxide and extracted with chloroform. The chloroform layer was washed with water and dried. After evaporating chloroform, the resulting residue was recrystallized from a mixture of benzene and hexane to give 1.4 g of 2-(2,2-diphenyl ethyl)-2-imidazoline having a melting point of 98° to 101° C. The hydrochloride thereof had a melting point of 173°-175° C.

後処理

  1. temperatureAfter cooling
  2. extractionextracted with chloroform
  3. washThe chloroform layer was washed with water
  4. customdried
  5. customAfter evaporating chloroform
  6. customthe resulting residue was recrystallized from a mixture of benzene and hexane

出典と根拠

ORDレコード
ord-46bc966e1cd8498b964d04d53e130357
出典データセット
uspto-grants-1979_01
特許番号
US04136188

反応ノート

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