反応式
[NH2:1][S:2]([C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([CH3:13])[CH:11]=2)[N:6]([CH3:14])[C:5]=1[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[O:3].[Mn]([O-])(=O)(=O)=[O:21].[Na+]>>[CH3:14][N:6]1[C:7]2[C:12](=[CH:11][C:10]([CH3:13])=[CH:9][CH:8]=2)[C:4]([S:2](=[O:21])(=[O:3])[NH2:1])=[C:5]1[C:15]([O:17][CH2:18][CH3:19])=[O:16]参加物
3
実験手順
8.0 gm (29 millimols) of ethyl 3-aminosulfinyl-1,5-dimethyl-indole-2-carboxylate were reacted analogous to Example 18(c) with 3.0 gm (19 millimols) of sodium permanganate to yield b 5.9 gm (70% of theory) of ethyl 1,5-dimethyl-3-sulfamoyl-indole-2-carboxylate, M.p.: 148° C., and 2.0 gm (28% of theory) of 4,7-dimethyl-2H-isothiazolo[4,5-b]-indole-3(2H)-one-1,1-dioxide; M.p.: 295° C. (decompositon).
出典と根拠
- ORDレコード
- ord-1201a7a8d3b8469584fda04156d0bcbb
- 出典データセット
- uspto-grants-1979_01
- 特許番号
- US04137313
関連ノート
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