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Toluene → 3-(4-Methyl-3-oxocyclohexyl)-butyraldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Toluene | HCID 1140 | — |
| 反応物 | (+)-Dihydrocarvone | HCID 22227 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 反応物 | HCID 178418416 | HCID 178418416 | — |
| 触媒 | Hexanoic acid, 2-ethyl-, rhodium(3+) salt (3:1) | HCID 89395 | — |
| 生成物 | 3-(4-Methyl-3-oxocyclohexyl)-butyraldehyde | HCID 14828908 | 86% |
反応手順
50 g of dihydrocarvone, 1.5 g of triphenylphosphene and 0.013 g of rhodium 2-ethylhexanoate are reacted as described in Example 1 in 200 ml of toluene at 150° C. and under 280 bar with a 1:1 mixture of hydrogen and carbon monoxide. The distillative working-up yields 51.5 g of 3-(4-methyl-3-oxocyclohexyl)-butyraldehyde (boiling point=98°-100° C./0.1 mbar, 86% of theory).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04505860 |
| 出典データセット | uspto-grants-1985_03 |
| ORD ID | ord-4387ec89b5434db88c9b85e05cc83f3b |
| 出典メモ | uspto-grants-1985_03 |