HCID 600389、化合物 → 5,8-Quinoxalinediol
反応式
C[O:2][C:3]1[CH:12]=[CH:11][C:10]([O:13]C)=[C:9]2[C:4]=1[N:5]=[CH:6][CH:7]=[N:8]2.[Cl-].[Al+3].[Cl-].[Cl-]>C1C=CC=CC=1>[OH:13][C:10]1[CH:11]=[CH:12][C:3]([OH:2])=[C:4]2[C:9]=1[N:8]=[CH:7][CH:6]=[N:5]2参加物
4
実験手順
4 g (0.021 mol) of 5,8-dimethoxyquinoxaline was refluxed for 2 hours under heating in 50 ml of benzene together with 20 g of aluminum chloride. After allowing to cool to room temperature, the reaction solution was extracted with ethyl acetate, and the extract was dried and concentrated. Recrystallization of the residue from ethyl acetate gave 2.4 g (71%) of the end product. m.p. 234°-236° C.
後処理
- extractionthe reaction solution was extracted with ethyl acetate
- customthe extract was dried
- concentrationconcentrated
- customRecrystallization of the residue from ethyl acetate
出典と根拠
- ORDレコード
- ord-0486eac9e00d4128b2775f52815d369e
- 出典データセット
- uspto-grants-1985_03
- 特許番号
- US04506001
反応ノート
読み込み中…