beta-Glycerophosphate → HCID 131714170、化合物

関与物質

反応条件

反応手順

To a 50% aqueous solution of β-glycerophosphoric acid (4.8 g) at ambient temperature with stirring was added 1-[-1,3-dichloro-6-trifluoromethyl-9-phenanthryl]-3-di(n-butyl)aminopropanol (14.0 g). To the mixture was added ethanol (500 ml) and the mixture is heated to about 100° C. to affect solution. The solution is then filtered and the ethanol removed under vacuum until the desired product precipitates as a white crystalline material. After collecting and drying, the desired product has a melting point of 60°-65° C. Elemental analysis is as follows: Calculated C, 51.78; H, 5.80; N, 2.08 and Cl, 10.56 Found C, 51.83; H, 5.65; N, 2.10 and Cl, 10.20.

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