関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Benzoyl chloride, 3,4-dichloro- | HCID 76403 | — |
| 反応物 | N'-t-butyl-N-(2-pyridinecarbonyl)hydrazine | HCID 15767542 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | N'-t-butyl-N-(2-pyridinecarbonyl)-N'-(3,4-dichlorobenzoyl)hydrazine | HCID 15767546 | 79.1% |
反応手順
A solution of N'-t-butyl-N-(2-pyridinecarbonyl)-hydrazine (0.5 g) in 10 ml of toluene was treated with 50% sodium hydroxide (0.61 g). 3,4-Dichlorobenzoyl chloride (0.6 g) was added and the mixture was stirred rapidly for 4 hours at 23° C. and then was allowed to stand for 48 hours. The solids were removed by filtration and washed with water to afford 0.75 g of N'-t-butyl-N-(2-pyridinecarbonyl)-N'-(3,4-dichlorobenzoyl)hydrazine as a white solid: m.p. 175°-178° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05424333 |
|---|
| 出典データセット | uspto-grants-1995_06 |
|---|
| ORD ID | ord-18c27fb958a94b719c536689407476d8 |
|---|
| 出典メモ | uspto-grants-1995_06 |
|---|
