Chlorine → 2,3-Dichloro-5-(trichloromethyl)pyridine

HRID 2164888ノート

反応式

HRID 2164888 の反応式
[Cl:1]C(C1C=CC=CN=1)(Cl)Cl.[Cl:11][C:12]1[N:17]=[CH:16][C:15]([C:18]([Cl:21])([Cl:20])[Cl:19])=[CH:14][C:13]=1C(Cl)(Cl)Cl.ClCl>>[Cl:1][C:13]1[CH:14]=[C:15]([C:18]([Cl:21])([Cl:20])[Cl:19])[CH:16]=[N:17][C:12]=1[Cl:11]

参加物

4

反応物 3

HCID 24526ChlorineHCID 1232152-(Trichloromethyl)pyridineHCID 133826392-Chloro-3,5-bis(trichloromethyl)pyridine

生成物 1

HCID 946472,3-Dichloro-5-(trichloromethyl)pyridine

実験手順

Seventy-five grams of a mixture containing 24.3% 3,5-bis(trichloromethyl pyridine and 6.5% 6-chloro-3,5-bis(trichloromethyl)pyridine were chlorinated with 70 grams per hour of chlorine at 190° C. for 8 hours. Analysis is listed in Table 8. The 5,6-dichloro-3-trichloromethyl pyridine concentration went from zero to 0.5% and the 2,6-dichloro-3,5-bis(trichloromethyl)pyridine went from zero to 0.7%. The 3,5-bis(trichloromethyl)pyridine went from 24.3% to 18.1% while the 6-chloro-3,5-bis(trichloromethyl)pyridine increased from 6.5% to 14.0%. Temperatures below 190° C. give unacceptably slow reaction rates to produce 5,6-dichloro-3-trichloromethyl pyridine and 2,3,5,6-tetrachloropyriidine.

後処理

  1. concentrationThe 5,6-dichloro-3-trichloromethyl pyridine concentration
  2. temperatureincreased from 6.5% to 14.0%
  3. customTemperatures below 190° C. give unacceptably slow
  4. customreaction rates

出典と根拠

ORDレコード
ord-269c154340ca4ee1ab50e34d9431bef0
出典データセット
uspto-grants-1985_03
特許番号
US04507486

反応ノート

読み込み中…