HCID 23044549、化合物 → HCID 131716457、化合物
反応式
[Cl:1][CH2:2][CH:3]1[O:7]C=[N:5][CH:4]1[C:8]([NH2:10])=[O:9]>Cl>[ClH:1].[Cl:1][CH2:2][CH:3]([OH:7])[CH:4]([C:8]([NH2:10])=[O:9])[NH2:5]参加物
3
反応条件
- 温度
- 50 °C
実験手順
5-(Chloromethyl)-4,5-dihydro-4-oxazolecarboxamide was dissolved in 1500 ml of 2N hydrochloric acid and warmed to 50° C. for 2 hours. The hydrochloric acid was removed in vacuo and the residue was triturated with isopropanol to yield the title compound as brownish crystals; yield 133.9 g.
後処理
- customThe hydrochloric acid was removed in vacuo
- customthe residue was triturated with isopropanol
出典と根拠
- ORDレコード
- ord-95f3abde35e6494890f64eef7719b935
- 出典データセット
- uspto-grants-1990_07
- 特許番号
- US04939253
反応ノート
読み込み中…