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1,3-Propanediol, 2-methylene- → 3-Hexadecylaminothiocarbonyloxy-2-methylenepropan-1-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,3-Propanediol, 2-methylene- | HCID 77048 | — |
| 反応物 | Hexadecyl isothiocyanate | HCID 138233 | — |
| 触媒 | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 3-Hexadecylaminothiocarbonyloxy-2-methylenepropan-1-ol | HCID 54063336 | — |
反応手順
Hexadecyl isothiocyanate (9.65 g) and 2-methylenepropane-1,3-diol) (3.0 g) were heated with pyridine (17 ml) and 4-dimethylaminopyridine (0.8 g) to 104° C. for 6.5 hours. The mixture was evaporated to dryness in vacuo and chromatographed on a Waters PrepLC®/System 500A using a PrepPAK®-500/SILICA cartridge with ether/chloroform/hexane 2:2:9 as eluent.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04945098 |
| 出典データセット | uspto-grants-1990_07 |
| ORD ID | ord-818d377f8cbf4779a998dd70ca11179a |
| 出典メモ | uspto-grants-1990_07 |