関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1,4-Dioxane | HCID 31275 | — |
| 反応物 | N-Allylglycine | HCID 76651 | — |
| 反応物 | 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile | HCID 93865 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 溶媒 | Triethylamine | HCID 8471 | — |
| 生成物 | N-BOC allylglycine | HCID 86738924 | — |
反応手順
A mixture of 884 mg of allylglycine, 4.6 ml of water, 4.6 ml of dioxane, 1.6 ml of triethylamine and 2.08 g BOC-ON is stirred for 3.75 hrs at 25° C. Then 15 ml of water and 20 ml of ether are added. The aqueous layer is separated, washed with ether, acidified to pH 2 with HCl, and filtered to isolate the crystalline product, 1.4. g, m.p. 109° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04388475 |
|---|
| 出典データセット | uspto-grants-1983_06 |
|---|
| ORD ID | ord-cc727055b1e44529803bfeb0e8302f14 |
|---|
| 出典メモ | uspto-grants-1983_06 |
|---|
