Ethanol hydrochloride → HCID 136351074、化合物

反応式

[OH:1][C:2]1[C:9]([O:10][CH2:11][CH2:12][O:13][CH2:14][CH2:15][O:16][CH3:17])=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH3:18][CH2:19][OH:20].[ClH:21]>>[ClH:21].[OH:1][C:2]1[C:9]([O:10][CH2:11][CH2:12][O:13][CH2:14][CH2:15][O:16][CH3:17])=[CH:8][CH:7]=[CH:6][C:3]=1[C:4](=[NH:5])[O:20][CH2:19][CH3:18]

参加物

反応物 2

HCID 21887872Ethanol hydrochloride

HCID 58506482HCID 58506482、化合物

生成物 1

HCID 136351074HCID 136351074、化合物

実験手順

A solution of 2-hydroxy-3-(2-(2-methoxyethoxy)ethoxy)benzonitrile (6 g) in EtOH/HCl (g) (150 mL) was heated to 40° C. overnight in a sealed tube. The solvent was evaporated under vacuum and the residue (7 g, crude) was used for the next step without further purification.

後処理

customThe solvent was evaporated under vacuum
customthe residue (7 g, crude) was used for the next step without further purification

出典と根拠

ORDレコード: ord-f4064b5af8634a8d83c77c9e1cbd28a0
出典データセット: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09045440B2

反応ノート

読み込み中…

参加物