化工社化工社 化学情報印刷レポート · 研究参考用
Sodium borohydride → (8-Methyl-2-o-tolylquinolin-3-yl)methanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 反応物 | 8-Methyl-2-o-tolylquinoline-3-carbaldehyde | HCID 57707895 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | (8-Methyl-2-o-tolylquinolin-3-yl)methanol | HCID 57707986 | — |
反応手順
Prepared according to Procedure B using 8-methyl-2-o-tolylquinoline-3-carbaldehyde (1.28 g, 4.9 mmol) and solid NaBH4 (278 mg, 1.5 eq) in THF (10 mL). After purification, (8-methyl-2-o-tolylquinolin-3-yl)methanol was obtained as white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08193199B2 |
| 出典データセット | uspto-grants-2012_06 |
| ORD ID | ord-883701b19faf4168bee54f6a39eb4754 |
| 出典メモ | uspto-grants-2012_06 |