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Ethyl 5-bromopyrazolo[1,5-a]pyridine-3-carboxylate → Ethyl 5-(2-(7-fluoro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyridine-3-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl 5-bromopyrazolo[1,5-a]pyridine-3-carboxylate | HCID 53249841 | — |
| 反応物 | 2-(7-Fluoro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)pyrrolidine | HCID 89618276 | — |
| 生成物 | Ethyl 5-(2-(7-fluoro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyridine-3-carboxylate | HCID 89635801 | — |
反応手順
The title compound (Int-65) was prepared by the method similar to that of Int-84 using 2-(7-fluoro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)pyrrolidine (Int-56B)) and Ethyl 5-bromopyrazolo[1,5-a]pyridine-3-carboxylate to afford as pale brown solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09045478B2 |
| 出典データセット | uspto-grants-2015_06 |
| ORD ID | ord-50a79f2e4476454088b428f27a31fae5 |
| 出典メモ | uspto-grants-2015_06 |