関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1H-1,2,4-Triazole | HCID 9257 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 2-Fluoro-5-nitropyridine | HCID 95264 | — |
| 生成物 | 5-nitro-2-(1H-1,2,4-triazol-1-yl)pyridine | HCID 2766764 | — |
反応手順
2-fluoro-5-nitropyridine (30 g, 18.9 mmol) was added to a stirred solution of 1H-1,2,4-triazole (1.566 g, 22.7 mmol) and K2CO3 (5.14 g, 37.8 mmol) and stirred for 16 hrs at 25° C. Reaction mass was diluted with ice cold water and stirred for 15 min. The solid obtained was filtered and dried under vacuum to afford the desired product. MS (ESI): m/z 192 (M+H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09045479B2 |
|---|
| 出典データセット | uspto-grants-2015_06 |
|---|
| ORD ID | ord-fe1dabd14ff74e529d27d0fbafe163ee |
|---|
| 出典メモ | uspto-grants-2015_06 |
|---|
