Acetic Anhydride → Methyl 2-(acetylamino)-7-methoxy-3-oxoheptanoate
反応式
O[N:2]=[C:3]([C:8](=[O:15])[CH2:9][CH2:10][CH2:11][CH2:12][O:13][CH3:14])[C:4]([O:6][CH3:7])=[O:5].[C:16](OC(=O)C)(=[O:18])[CH3:17]>C(O)(=O)C.[C].[Pd]>[C:16]([NH:2][CH:3]([C:8](=[O:15])[CH2:9][CH2:10][CH2:11][CH2:12][O:13][CH3:14])[C:4]([O:6][CH3:7])=[O:5])(=[O:18])[CH3:17]参加物
5
実験手順
Methyl 2-(hydroxyimino)-7-methoxy-3-oxoheptanoate (5.70 g) and palladium-carbon (900 mg) were suspended in acetic acid (60 ml)-acetic anhydride (25 ml) and the mixture was stirred under a hydrogen atmosphere (1 atom) at room temperature for 14 hr. The palladium catalyst was filtered off, and the filtrate was concentrated under reduced pressure to give the object product (5.48 g).
後処理
- filtrationThe palladium catalyst was filtered off
- concentrationthe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-23c7ad32920849b3a6eef983371b1807
- 出典データセット
- uspto-grants-2015_06
- 特許番号
- US09045436B2
反応ノート
読み込み中…