2-(Isopropylamino)ethanol → N-(2-((tert-butyldimethylsilyl)oxy)ethyl)propan-2-amine
反応式
[CH:1]([NH:4][CH2:5][CH2:6][OH:7])([CH3:3])[CH3:2].[C:8]([Si:12](Cl)([CH3:14])[CH3:13])([CH3:11])([CH3:10])[CH3:9].[Si](OCCNC)(C(C)(C)C)(C)C>>[Si:12]([O:7][CH2:6][CH2:5][NH:4][CH:1]([CH3:3])[CH3:2])([C:8]([CH3:11])([CH3:10])[CH3:9])([CH3:14])[CH3:13]参加物
4
実験手順
[2-(tert-Butyl-dimethylsilanyloxy)-ethyl]-isopropyl-amine (8-b) (20 gm, 37.4%) was synthesized as a yellow liquid from 2-isopropylamino-ethanol (18-b) (25 g, 242.31 mmol) and tert-butyl-chloro-dimethyl-silane (25.5 g, 242.31 mmol) following the procedure as described for [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-methyl-amine (8-a).
出典と根拠
- ORDレコード
- ord-6d1844a642a94b798d4c6f7abfcfd69c
- 出典データセット
- uspto-grants-2015_06
- 特許番号
- US09045486B2
反応ノート
読み込み中…