Methanesulfonic acid 1-(2,5-dichlorophenyl)-cyclopentylmethyl ester → Methanesulfonic acid 1-naphthalen-2-yl-cyclopentylmethyl ester

HRID 2169258ノート

反応式

HRID 2169258 の反応式
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]1([CH2:16][OH:17])[CH2:15][CH2:14][CH2:13][CH2:12]1.ClC1C=CC(Cl)=CC=1C1(C[O:32][S:33]([CH3:36])(=O)=[O:34])CCCC1>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]1([CH2:16][O:17][S:33]([CH3:36])(=[O:34])=[O:32])[CH2:15][CH2:14][CH2:13][CH2:12]1

参加物

3

反応物 2

HCID 86725896Methanesulfonic acid 1-(2,5-dichlorophenyl)-cyclopentylmethyl esterHCID 86725908(1-Naphthalen-2-yl-cyclopentyl)-methanol

生成物 1

HCID 86725909Methanesulfonic acid 1-naphthalen-2-yl-cyclopentylmethyl ester収率 54%

実験手順

Methanesulfonic acid 1-naphthalen-2-yl-cyclopentylmethyl ester (214) (16.0 g, 54.0%) was synthesized as a white solid from (1-naphthalen-2-yl-cyclopentyl)-methanol (213) (22.0 g, 97.34 mmol) following the procedure described for methanesulfonic acid 1-(2,5-dichlorophenyl)-cyclopentylmethyl ester (201).

出典と根拠

ORDレコード
ord-55f87dfe5db8478abbf21253edd321c0
出典データセット
uspto-grants-2015_06
特許番号
US09045486B2

反応ノート

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