2-[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-acetamidine hydrochloride → 2-(1-(3-Chlorophenyl)-cyclopentyl)-acetamidine hydrochloride

HRID 2169520ノート

反応式

HRID 2169520 の反応式
[Cl:1]C1C=C(C2(CC#N)CCCC2)C=CC=1.[ClH:16].FC(F)(F)[C:19]1[CH:24]=[CH:23][C:22]([C:25]2([CH2:30][C:31]([NH2:33])=[NH:32])[CH2:29][CH2:28][CH2:27][CH2:26]2)=[CH:21][CH:20]=1>>[ClH:1].[Cl:16][C:24]1[CH:23]=[C:22]([C:25]2([CH2:30][C:31]([NH2:33])=[NH:32])[CH2:29][CH2:28][CH2:27][CH2:26]2)[CH:21]=[CH:20][CH:19]=1

参加物

3

反応物 2

HCID 867261312-[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-acetamidine hydrochlorideHCID 867261402-(1-(3-Chlorophenyl)cyclopentyl)acetonitrile

生成物 1

HCID 867261412-(1-(3-Chlorophenyl)-cyclopentyl)-acetamidine hydrochloride

実験手順

2-(1-(3-Chlorophenyl)-cyclopentyl)-acetamidine hydrochloride (499) was synthesized from 2-(1-(3-chlorophenyl)cyclopentyl)acetonitrile (498) following the procedure described for HCl-salt of 2-[1-(4-trifluoromethyl-phenyl)-cyclopentyl]-acetamidine hydrochloride (242).

出典と根拠

ORDレコード
ord-49db03d5e297462c9756c981250b87eb
出典データセット
uspto-grants-2015_06
特許番号
US09045486B2

反応ノート

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