2-Fluoro-5-(hydroxymethyl)benzonitrile → 2-Fluoro-5-(((1,2,2-trimethyl-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidin-7-yl)oxy)methyl)benzonitrile
反応式
[F:1][C:2]1[CH:9]=[CH:8][C:7]([CH2:10][OH:11])=[CH:6][C:3]=1[C:4]#[N:5].Cl[C:13]1[CH:14]=[C:15]2[N:22]([CH3:23])[C:21]([CH3:25])([CH3:24])[CH2:20][N:16]2[C:17](=[O:19])[N:18]=1>>[F:1][C:2]1[CH:9]=[CH:8][C:7]([CH2:10][O:11][C:13]2[CH:14]=[C:15]3[N:22]([CH3:23])[C:21]([CH3:25])([CH3:24])[CH2:20][N:16]3[C:17](=[O:19])[N:18]=2)=[CH:6][C:3]=1[C:4]#[N:5]参加物
3
実験手順
The title compound was prepared by a procedure similar to that described for E9 starting from 2-fluoro-5-(hydroxymethyl)benzonitrile and 7-chloro-1,2,2-trimethyl-2,3-dihydroi-midazo[1,2-c]pyrimidin-5(1H)-one.
出典と根拠
- ORDレコード
- ord-a6d6b7d922b043c9bcabdfaa177ebecc
- 出典データセット
- uspto-grants-2015_06
- 特許番号
- US09051325B2
反応ノート
読み込み中…