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Hydracrylonitrile → Bis(2-cyanoethyl) phosphorochloridite
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydracrylonitrile | HCID 8011 | — |
| 反応物 | Tetrahydrofuran | HCID 8028 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Phosphorus trichloride | HCID 24387 | — |
| 生成物 | Bis(2-cyanoethyl) phosphorochloridite | HCID 11390133 | — |
反応手順
In the second reaction vessel 3-hydroxypropionitrile (20 mmol) and triethylamine (2.8 mL, 20 mmol) were added to a solution of phosphorus trichloride (10 mmol) in THF (25 mL) under dry nitrogen. The mixture was stirred for 10 min at room temperature to give bis(2-cyanoethyl) phosphorochloridite (28).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08193384B2 |
| 出典データセット | uspto-grants-2012_06 |
| ORD ID | ord-07a034ec63f6492a84428633fd197f33 |
| 出典メモ | uspto-grants-2012_06 |