関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Sodium Cyanide | HCID 8929 | — |
| 反応物 | Trivinyl(3-chloropropyl)silane | HCID 23630656 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 3-Cyanopropyltrivinylsilane | HCID 57945605 | 86.2% |
反応手順
Compound 3-chloropropyltrivinylsilane (1000 mg, 5.35 mmol) and sodium cyanide (525 mg, 10.70 mmol) were dissolved in 18 ml of dimethylformamide, and the mixture was heated at 70° C. for 4 hours. After the reaction, the organic layer was extracted after addition of distilled water and ether, and then purified by column chromatography (n-Hex:EA=10:1, Rf=0.42), to give 818 mg (86% yield) of pure 3-cyanopropyltrivinylsilane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08197903B2 |
|---|
| 出典データセット | uspto-grants-2012_06 |
|---|
| ORD ID | ord-6de4cb8820464af5bd48ac5f26ac22a1 |
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| 出典メモ | uspto-grants-2012_06 |
|---|
