Thiophenol → Methyl 3-bromo-6-(phenylthiomethyl)-2-methoxybenzoate

反応式

BrC1C(OC)=C(C=CC=1C[S:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1C)C(OCC)=O.[Br:24][C:25]1[C:26]([O:37][CH3:38])=[C:27]([C:32]([CH2:35]Br)=[CH:33][CH:34]=1)[C:28]([O:30][CH3:31])=[O:29].C1(S)C=CC=CC=1>>[Br:24][C:25]1[C:26]([O:37][CH3:38])=[C:27]([C:32]([CH2:35][S:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:33][CH:34]=1)[C:28]([O:30][CH3:31])=[O:29]

参加物

反応物 3

HCID 7969Thiophenol

HCID 66685947Methyl 3-bromo-6-bromomethyl-2-methoxybenzoate2 回

HCID 67107587Ethyl 3-bromo-2-methoxy-(2-methylphenylthiomethyl)benzoate

生成物 1

HCID 67107558Methyl 3-bromo-6-(phenylthiomethyl)-2-methoxybenzoate

実験手順

Prepared by proceeding in a similar manner to Intermediate 77, starting from methyl 3-bromo-6-bromomethyl-2-methoxybenzoate (Intermediate 89) and thiophenol and used without further characterization.

後処理

customPrepared

出典と根拠

ORDレコード: ord-92a985f3592b48198eb145b67b2426b7
出典データセット: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09067905B2

反応ノート

読み込み中…