化工社化工社 化学情報印刷レポート · 研究参考用
1-Chloro-4-isocyanato-2-(trifluoromethyl) benzene → 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(2,3-dioxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)urea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Chloro-4-isocyanato-2-(trifluoromethyl) benzene | HCID 2733265 | — |
| 反応物 | 8-(4-aminophenoxy)pyrido[2,3-b]pyrazine-2,3(1H,4H)-dione | HCID 59588844 | — |
| 生成物 | 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(2,3-dioxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)urea | HCID 44133544 | 38% |
反応手順
Method F2 was used with 8-(4-aminophenoxy)pyrido[2,3-b]pyrazine-2,3(1H,4H)-dione and 4-chloro-3-trifluoromethylphenyl isocyanate to obtain the title compound (yield 38%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08198279B2 |
| 出典データセット | uspto-grants-2012_06 |
| ORD ID | ord-7c23065b1aab43a0a250fbc425f18e1c |
| 出典メモ | uspto-grants-2012_06 |