化工社化工社 化学情報印刷レポート · 研究参考用
Benzylamine → N-[4-(Methylthio)phenyl]benzenemethanamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzylamine | HCID 7504 | — |
| 反応物 | 4-Bromothioanisole | HCID 66037 | — |
| 生成物 | N-[4-(Methylthio)phenyl]benzenemethanamine | HCID 9964622 | 88% |
反応手順
Using the general procedure, 4-bromothioanisole (203 mg, 1.0 mmol) was coupled with benzylamine (164 μL, 1.5 mmol). Purification of the crude product by column chromatography on silica gel using hexane/ethyl acetate (15:1) as eluent afforded the desired product as a white solid (201 mg, 88% yield). Rf=0.4 (hexane/ethyl acetate=10:1).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09067955B2 |
| 出典データセット | uspto-grants-2015_06 |
| ORD ID | ord-639a7cb68de8402a918f20d3f02831d7 |
| 出典メモ | uspto-grants-2015_06 |