Sulfuryl chloride → 6-Bromo-8-chloro-7-isopropoxy-2,2-dimethyl-chroman-4-one

HRID 2180460ノート

反応式

HRID 2180460 の反応式
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[O:12][CH:13]([CH3:15])[CH3:14])[O:8][C:7]([CH3:17])([CH3:16])[CH2:6][C:5]2=[O:18].S(Cl)([Cl:22])(=O)=O>ClCCl>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[C:10]([Cl:22])[C:11]=1[O:12][CH:13]([CH3:14])[CH3:15])[O:8][C:7]([CH3:16])([CH3:17])[CH2:6][C:5]2=[O:18]

参加物

4

反応物 2

HCID 24648Sulfuryl chlorideHCID 224909096-Bromo-7-isopropoxy-2,2-dimethyl-chroman-4-one2 回

生成物 1

HCID 224907866-Bromo-8-chloro-7-isopropoxy-2,2-dimethyl-chroman-4-one

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

Following General Procedure B, 6-bromo-7-isopropoxy-2,2-dimethyl-chroman-4-one, (Compound 6, 2.2 g, 7.0 mmol) and sulfuryl chloride (0.84 mL, 10.5 mmol) in dichloromethane were reacted to yield the title compound as white trapezoidal plates after recrystallization from hexanes.

後処理

  1. customwere reacted

出典と根拠

ORDレコード
ord-70fe9f8c19564365a39bda179e28725f
出典データセット
uspto-grants-2005_05
特許番号
US06887896B1

反応ノート

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