Water → 6-Bromo-3-nitro-2-pyridinamine
反応式
Br[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Br:11])[N:3]=1.[NH4+:12].C(O)C.O>C(O)C>[NH2:12][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Br:11])[N:3]=1参加物
5
実験手順
To a suspension of 2,6-dibromo-3-nitropyridine (5.00 g) in ethanol (10 ml) was added a solution (6.8 M, 15 ml) of ammonium/ethanol at room temperature, and the mixture was stirred at room temperature for 19 hr in a sealed container. Water (25 ml) was added to the reaction mixture, and the precipitate was collected by filtration and washed with ethanol. This was suspended in ethanol (55 ml), heated, and allowed to cool. The precipitate was collected by filtration to give 2-amino-6-bromo-3-nitropyridine as a yellow powder (3.19 g).
後処理
- filtrationthe precipitate was collected by filtration
- washwashed with ethanol
- temperatureheated
- temperatureto cool
- filtrationThe precipitate was collected by filtration
出典と根拠
- ORDレコード
- ord-bfe9759d303e4d61b5738c819b2e988f
- 出典データセット
- uspto-grants-2005_05
- 特許番号
- US06890934B2
反応ノート
読み込み中…