Potassium bis(trimethylsilyl)amide → HCID 23684418、化合物

HRID 2181372ノート

反応式

HRID 2181372 の反応式
[CH3:1][C:2]1[CH2:3][C:4]2[C:9]([CH:10]=1)=[C:8](C1C3C(=CC=CC=3)C=CC=1)[CH:7]=[CH:6][CH:5]=2.C[Si]([N-][Si](C)(C)C)(C)C.[K+:30]>C1(C)C=CC=CC=1>[CH3:10][C:2]1[CH:1]=[C:10]([C:2]2[CH-:3][C:4]3[C:9]([CH:1]=2)=[CH:8][CH:7]=[CH:6][CH:5]=3)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=1.[K+:30]

参加物

4

反応物 2

HCID 3251421Potassium bis(trimethylsilyl)amideHCID 177791321-(2-Methyl-1H-inden-4-yl)naphthalene

生成物 1

HCID 23684418HCID 23684418、化合物収率 228.5%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

2-Methyl-4-naphthylindene (1.00 g, 3.27 mmole) was dissolved in 20 ml of toluene, potassium bis(trimethylsilyl)amide (1.05 equivalent, 3.43 mmole, 0.684 g) was added and the reaction mixture was stirred at room temperature for 24 hours, during which a yellow solid precipitated. Hexane was added (20 ml) and the mixture was stirred for 2 h. The solid product was isolated by vacuum filtration through a medium porosity frit. The solid was pumped dry giving 1.10 g, 98 percent of the desired product.

後処理

  1. customprecipitated
  2. additionHexane was added (20 ml)
  3. stirringthe mixture was stirred for 2 h
  4. customThe solid product was isolated by vacuum filtration through a medium porosity frit
  5. customThe solid was pumped dry

出典と根拠

ORDレコード
ord-63f20820a90e4fd4832188ce3a77a961
出典データセット
uspto-grants-2005_05
特許番号
US06891005B2

反応ノート

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