反応式
F[C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[C:13]([F:15])[CH:12]=[CH:11][C:10]=1[CH:16]([NH:18][S:19]([C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([O:28][CH3:29])[CH:23]=1)(=[O:21])=[O:20])[CH3:17].C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[F:8][C:6]1[CH:5]=[CH:4][C:3]2[C:9]3[C:10]([CH:16]([CH3:17])[N:18]([S:19]([C:22]4[CH:27]=[CH:26][CH:25]=[C:24]([O:28][CH3:29])[CH:23]=4)(=[O:20])=[O:21])[C:2]=2[CH:7]=1)=[CH:11][CH:12]=[C:13]([F:15])[CH:14]=3参加物
4
実験手順
The title compound was prepared from N-[1-(2′,4′,5-trifluoro-1,1′-biphenyl-2-yl)ethyl]-3-methoxybenzenesulfonamide (234 mg, 0.55 mmol), anhydrous N,N-dimethylformamide (1 mL), and potassium carbonate (154 mg, 1.1 mmol) according to the procedure and in the same manner as described in Example 105, step d resulting in the isolation of 211 mg (95%) of a white solid. This material was used without further purification in Example 115, step c;
出典と根拠
- ORDレコード
- ord-bb10fe8a06b84534b34877521a316640
- 出典データセット
- uspto-grants-2005_05
- 特許番号
- US06894061B2
関連ノート
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