4-Hydrazinobenzoic acid → 4-(3,5-dimethyl-1H-pyrazol-1-yl)benzoic acid
反応式
[NH:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[CH:5][CH:4]=1)[NH2:2].[C:12]([CH2:15][C:16](=O)[CH3:17])(=O)[CH3:13]>C(O)C>[CH3:13][C:12]1[CH:15]=[C:16]([CH3:17])[N:1]([C:3]2[CH:4]=[CH:5][C:6]([C:7]([OH:9])=[O:8])=[CH:10][CH:11]=2)[N:2]=1参加物
4
実験手順
A solution of 4-hydrazino-benzoic acid (0.60 g, 3.95 mmol) and acetyl acetone (0.405 ml, 3.95 mmol) in ethanol (20 ml) refluxed for 1 hour. Ethanol was removed in vacuum and the remaining solid was triturated with water and collected by filtration to produce 285 (0.71 mg, 83% yield). [M−1]− 215.1.
後処理
- customEthanol was removed in vacuum
- customthe remaining solid was triturated with water
- filtrationcollected by filtration
出典と根拠
- ORDレコード
- ord-f63e7b74480545aba7a9ed071151bd6c
- 出典データセット
- uspto-grants-2005_05
- 特許番号
- US06897220B2
反応ノート
読み込み中…