Acetic Anhydride → 2-Acetoxy-3-methoxybenzaldehyde
反応式
[C:1](OC(=O)C)(=[O:3])[CH3:2].[CH3:8][O:9][C:10]1[CH:17]=[CH:16][CH:15]=[C:12]([CH:13]=[O:14])[C:11]=1[OH:18].C([O-])([O-])=O.[K+].[K+]>C(Cl)Cl>[C:1]([O:18][C:11]1[C:10]([O:9][CH3:8])=[CH:17][CH:16]=[CH:15][C:12]=1[CH:13]=[O:14])(=[O:3])[CH3:2]参加物
5
実験手順
Acetic anhydride (45.9 g, 0.45 mol) was added to a suspension of 3-methoxysalicylaldehyde (45.6 g, 0.3 mol) and K2CO3 (42.0 g, 0.6 mol) in CH2Cl2 (450 L) at rt. The reaction mixture was stirred at rt overnight then filtered, evaporated and the residue was recrystallised from cyclohexane to give 42 (42.0 g, 74%) as colourless needles:
後処理
- filtrationthen filtered
- customevaporated
- customthe residue was recrystallised from cyclohexane
出典と根拠
- ORDレコード
- ord-e4efdb52c67c4a0e99b2eef199743808
- 出典データセット
- uspto-grants-2012_06
- 特許番号
- US08198302B2
反応ノート
読み込み中…