HCID 9847377、化合物 → HCID 22458162、化合物
反応式
[CH:1]1([C:7]([N:9]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=2[O:35][C:36]([F:39])([F:38])[F:37])[CH2:10][CH2:11][N:12]2[CH2:17][CH2:16][N:15]([C:18]3[CH:23]=[CH:22][C:21]([N+:24]([O-])=O)=[CH:20][C:19]=3[O:27][CH3:28])[CH2:14][CH2:13]2)=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[N+](C1C=CC=CC=1N(C(C1CCCCC1)=O)CCN1CCN(C2C=CC=CC=2OC)CC1)([O-])=O>>[CH:1]1([C:7]([N:9]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=2[O:35][C:36]([F:38])([F:39])[F:37])[CH2:10][CH2:11][N:12]2[CH2:13][CH2:14][N:15]([C:18]3[CH:23]=[CH:22][C:21]([NH2:24])=[CH:20][C:19]=3[O:27][CH3:28])[CH2:16][CH2:17]2)=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1参加物
3
実験手順
The title compound was prepared according to the procedure reported in example 27, but substituting the compound of example 55 for the compound of example 2 and heating at reflux for 3 h. The residue was purified by flash chromatography (EtOAc). Yield: 58%.
後処理
- temperatureheating
- temperatureat reflux for 3 h
- customThe residue was purified by flash chromatography (EtOAc)
出典と根拠
- ORDレコード