1,2-Dichlorobenzene → HCID 22459170、化合物

HRID 2185041ノート

反応式

HRID 2185041 の反応式
C([O:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][CH:13]=2)=[CH:7][CH:6]=1)C=C.Cl[C:20]1[CH:25]=CC=C[C:21]=1Cl>>[CH3:18][C:15]1[CH:14]=[CH:13][C:12]([O:11][C:8]2[CH:7]=[CH:6][C:5]([OH:4])=[C:10]([CH2:25][CH:20]=[CH2:21])[CH:9]=2)=[CH:17][CH:16]=1

参加物

3

反応物 2

HCID 72391,2-DichlorobenzeneHCID 224588924-(4'-Methylphenoxy)phenyl allyl ether

生成物 1

HCID 22459170HCID 22459170、化合物

実験手順

4-(4′-Methylphenoxy)phenyl allyl ether (4.00 g, 16.37 mmol) was taken up in 1,2-dichlorobenzene (50 mL) and refluxed for 20 h. After cooling, the solvent was removed in vacuo and the resulting crude oil was chromatographed on silica gel (15% ethyl acetate hexane) to afford 4-(4′-methylphenoxy)-2-allylphenol.

後処理

  1. temperaturerefluxed for 20 h
  2. temperatureAfter cooling
  3. customthe solvent was removed in vacuo
  4. customthe resulting crude oil was chromatographed on silica gel (15% ethyl acetate hexane)

出典と根拠

ORDレコード
ord-b69a3b3c216a44a4aad0e200859f118e
出典データセット
uspto-grants-2002_06
特許番号
US06399640B1

反応ノート

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