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1,2,3,4-Tetrahydro-1-naphthoic acid → N-(6-isopropylpyridin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,2,3,4-Tetrahydro-1-naphthoic acid | HCID 12598146 | — |
| 反応物 | 6-(Propan-2-yl)pyridin-3-amine | HCID 17854288 | — |
| 生成物 | N-(6-isopropylpyridin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide | HCID 17854426 | 86.4% |
反応手順
By the reaction and treatment in the same manner as in Preparation Example 11 using 1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (1.51 g) and 5-amino-2-isopropylpyridine (1.17 g) as starting materials, N-(6-isopropylpyridin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (2.18 g) was obtained. melting point: 155.7° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08198454B2 |
| 出典データセット | uspto-grants-2012_06 |
| ORD ID | ord-059f4241356a4b3eacb0ba0fe5a8db36 |
| 出典メモ | uspto-grants-2012_06 |