Hydrochloric Acid → 1-(4-Chlorophenyl)-3-methyl-1H-pyrazole

反応式

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][NH2:9])=[CH:4][CH:3]=1.Cl.[C:11]1(NN)[CH:16]=CC=[CH:13][CH:12]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:16]=[CH:11][C:12]([CH3:13])=[N:9]2)=[CH:4][CH:3]=1

参加物

反応物 3

HCID 313Hydrochloric Acid

HCID 7516Phenylhydrazine

HCID 70624(4-Chlorophenyl)hydrazine

生成物 1

HCID 179399681-(4-Chlorophenyl)-3-methyl-1H-pyrazole

実験手順

This compound was prepared by the same methodology described for EXAMPLE 8 with 4-chlorophenyl hydrazine.HCl substituted for phenyl hydrazine and 2-amino-5-(2-N-t-butylaminosulfonylphenyl)pyridine was used in the coupling step. There was obtained the title compound; HRMS (M+H)+: calc. 468.089714; found 468.088873.

後処理

customThis compound was prepared by the same methodology

出典と根拠

ORDレコード: ord-3e6cac7adaf14a039318a865c2735d71
出典データセット: uspto-grants-2002_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06403620B1

反応ノート

読み込み中…