Benzene → Acetyl Tributyl Citrate

HRID 2186543

反応式

HRID 2186543 の反応式
[C:1]([OH:13])(=[O:12])[CH2:2][C:3]([CH2:8][C:9]([OH:11])=[O:10])([C:5]([OH:7])=[O:6])[OH:4].[CH:14]1[CH:19]=[CH:18][CH:17]=CC=1.[CH2:20]([OH:22])[CH3:21].[OH-].[K+]>[Sn].C(OCCCC)(=O)C.C(O)CCC>[CH3:17][CH2:18][CH2:19][CH2:14][O:10][C:9]([CH2:8][C:3]([O:4][C:20]([CH3:21])=[O:22])([C:5]([O:7][CH2:14][CH2:19][CH2:18][CH3:17])=[O:6])[CH2:2][C:1]([O:13][CH2:1][CH2:2][CH2:3][CH3:5])=[O:12])=[O:11]

参加物

8

反応物 4

HCID 241BenzeneHCID 311Citric AcidHCID 702EthanolHCID 14797Potassium Hydroxide

生成物 1

HCID 6505Acetyl Tributyl Citrate

試薬・触媒・溶媒 3

HCID 5352426Tin atom触媒HCID 2631-Butanol溶媒HCID 31272Butyl Acetate溶媒

反応条件

温度
150 °C

実験手順

German Pat. No. 1 041 944 describes a process in which a citric acid ester is said to be prepared from a crude citric acid broth. Specifically, the authors describe a process for producing an ester of citric acid, in which a raw 30% citric acid broth is dehydrated with benzene and ethanol to a syrup. Butanol and butyl acetate, along with a tin catalyst, are added to the syrup and the mixture is heated to a temperature of 140-160° C., whereupon the reaction is halted with potassium hydroxide. The resulting reaction product is washed with sodium carbonate in water, and the crude mixture distilled. The authors report yielding acetyl tributyl citrate in the recovered material.

後処理

  1. customThe resulting reaction product
  2. washis washed with sodium carbonate in water
  3. distillationthe crude mixture distilled

出典と根拠

ORDレコード
ord-bae6427c73664c1d8c019b4c4dc77073
出典データセット
uspto-grants-2002_06
特許番号
US06403825B1

関連ノート

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