Ethanol → Ethyl 7-bromo-3-hydroxy-2-naphthoate
反応式
[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[C:7]([OH:15])[C:8]([C:12]([OH:14])=[O:13])=[CH:9]2)=[CH:4][CH:3]=1.O.C([O-])(O)=O.[Na+].[CH3:22][CH2:23]O>S(=O)(=O)(O)O>[CH2:22]([O:13][C:12]([C:8]1[C:7]([OH:15])=[CH:6][C:5]2[C:10](=[CH:11][C:2]([Br:1])=[CH:3][CH:4]=2)[CH:9]=1)=[O:14])[CH3:23]参加物
6
実験手順
A solution of 81 g (0.3 mol) of 7-bromo-3-hydroxy-2-naphthoic acid in 600 ml dried EtOH and 60 ml conc. sulfuric acid was heated at reflux for 16 hours. The mixture was cooled to room temperature and treated with water (4000 ml) and neutralised with NaHCO3. The solid was separated by filtration and dried in a drying chamber afforded 75.3 g (85%) of the titled compound.
後処理
- temperatureat reflux for 16 hours
- customThe solid was separated by filtration
- customdried in a drying chamber
出典と根拠
- ORDレコード
- ord-f978a3687f9544378fc42058e1d9924b
- 出典データセット
- uspto-grants-2002_06
- 特許番号
- US06410562B1
反応ノート
読み込み中…