Hydrochloric Acid → Hydrochloric Acid

HRID 2187933ノート

反応式

HRID 2187933 の反応式
[CH2:1]([O:8][C:9]1[CH:16]=[CH:15][C:12]([C:13]#[N:14])=[CH:11][C:10]=1[O:17][CH2:18][CH2:19][NH:20]C(OC(C)(C)C)=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:28]>O1CCOCC1>[ClH:28].[NH2:20][CH2:19][CH2:18][O:17][C:10]1[CH:11]=[C:12]([CH:15]=[CH:16][C:9]=1[O:8][CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[C:13]#[N:14]

参加物

5

反応物 2

HCID 313Hydrochloric AcidHCID 226451464-Benzyloxy-3-[2-(t-butoxycarbonylamino)ethoxy]benzonitrile

生成物 2

HCID 313Hydrochloric AcidHCID 226451763-(2-Aminoethoxy)-4-benzyloxybenzonitrile

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

3.4 g (9.2 mmol) of 4-benzyloxy-3-[2-(t-butoxycarbonylamino)ethoxy]benzonitrile was dissolved in 40 ml of 4 N solution of hydrogen chloride in dioxane, and the obtained solution was stirred overnight. The solvent was evaporated to obtain hydrochloride of the crude title compound.

後処理

  1. customThe solvent was evaporated

出典と根拠

ORDレコード
ord-35dbfe6d105a47319274c772424495a8
出典データセット
uspto-grants-2002_06
特許番号
US06410538B2

反応ノート

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