化工社化工社 化学情報印刷レポート · 研究参考用
Imidazole → 5-(t-Butyldimethylsiloxy)-3-pentyne
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Imidazole | HCID 795 | — |
| 反応物 | 3-Butyn-1-OL | HCID 13566 | — |
| 反応物 | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 5-(t-Butyldimethylsiloxy)-3-pentyne | HCID 11019857 | — |
反応手順
To a solution of 3-butyn-1-ol (g) (10.0 g) in DMF (80 ml) were added t-butyldimethylsilyl chloride (21.5 g) and imidazol (10.6 g), and the resultant mixture was kept at 35° C. for 7 hours. The reaction mixture was treated in the conventional manner and the obtained crude product was distilled to give the title compound (h).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05426115 |
| 出典データセット | uspto-grants-1995_06 |
| ORD ID | ord-f6de6665a81f41a69e382a42c905148e |
| 出典メモ | uspto-grants-1995_06 |