2-Chlorobenzenesulfonyl chloride → HCID 59578028、化合物
反応式
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[Cl:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[S:23](Cl)(=[O:25])=[O:24].[CH2:27]([N:29]1[CH:37]=[C:36]2[C:31]([CH:32]=[CH:33][C:34]([NH2:38])=[CH:35]2)=[N:30]1)[CH3:28]>>[Cl:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[S:23]([N:9]1[CH2:8][CH2:7][C:6]2([C:4](=[O:5])[N:38]([C:34]3[CH:33]=[CH:32][C:31]4[C:36](=[CH:37][N:29]([CH2:27][CH3:28])[N:30]=4)[CH:35]=3)[CH2:13][CH2:12]2)[CH2:11][CH2:10]1)(=[O:25])=[O:24]参加物
4
実験手順
Off-white crystalline solid. MS (ESI): 473.1 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 2-chlorobenzenesulfonyl chloride and 2-ethyl-2H-indazol-5-ylamine (for synthesis: Kamel et al.; Journal fuer Praktische Chemie, 31; 1966; 100).
出典と根拠
- ORDレコード