化工社化工社 化学情報印刷レポート · 研究参考用
5-Methyl-1,2-oxazole-4-sulfonyl chloride → 8-(5-Methyl-isoxazole-4-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Methyl-1,2-oxazole-4-sulfonyl chloride | HCID 2776141 | — |
| 反応物 | 2-(4-Trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one acetic acid salt | HCID 66787333 | — |
| 生成物 | 8-(5-Methyl-isoxazole-4-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one | HCID 59577999 | — |
反応手順
The title compound was prepared in analogy to example 180 step D from 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one acetic acid salt (described in example 180 step C) and 5-methyl-isoxazole-4-sulfonyl chloride. White solid. MS (ESI): 460.3 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08329904B2 |
| 出典データセット | uspto-grants-2012_12 |
| ORD ID | ord-21f3c9c489fa44ccbe734e4bf4ca2459 |
| 出典メモ | uspto-grants-2012_12 |