1-Ethynyl-3-fluorobenzene → 4-[4-(3-fluoro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1-methyl-1H-pyridin-2-one
反応式
I[C:2]1[N:3]=[C:4]([CH3:16])[N:5]([C:8]2[CH:13]=[CH:12][N:11]([CH3:14])[C:10](=[O:15])[CH:9]=2)[C:6]=1[CH3:7].[C:17]([C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([F:25])[CH:20]=1)#[CH:18]>>[F:25][C:21]1[CH:20]=[C:19]([C:17]#[C:18][C:2]2[N:3]=[C:4]([CH3:16])[N:5]([C:8]3[CH:13]=[CH:12][N:11]([CH3:14])[C:10](=[O:15])[CH:9]=3)[C:6]=2[CH3:7])[CH:24]=[CH:23][CH:22]=1参加物
3
実験手順
The title compound, brown waxy solid, MS: m/e=322.1 (M+H+), was prepared in accordance with the general method of example 1c from 4-(4-iodo-2,5-dimethyl-imidazol-1-yl)-1-methyl-1H-pyridin-2-one and 1-Ethynyl-3-fluoro-benzene.
出典と根拠
- ORDレコード
- ord-2d45fe685a7c4f0b8f865e2983a19c4e
- 出典データセット
- uspto-grants-2012_12
- 特許番号
- US08334287B2
反応ノート
読み込み中…